Bipolar disorder

What would you think if your acquaintance suddenly quit his job as an office clerk, rented a barn for his five new classic cars and from now on wanted to earn his money by restoring old cars? You would probably call him crazy. In a way, you might be right. Because this is exactly the cliché of people who are going through a manic phase.

A life between ups and downs

Mania is one pole of bipolar disorder. The opposite pole is depression. This is a so-called "affective disorder", since it is primarily the emotional sensation that is impaired. The two opposite mood states occur alternately over individually varying periods of time.

Between the manic and depressive episodes, there are phases in which the affected person lives symptom-free. Their mood is then as constant as yours and mine. How long this symptom-free period lasts varies greatly from individual to individual. Anything from a few days to several years is possible. In addition, the rhythm changes in the course of the disease. However, the manic phases are always shorter than the depressive ones. By now, you're probably wondering what these manic and depressive episodes actually look like. For example like this:

I own the world!

About one third of those affected experience a feeling of great euphoria during manic phases. In the remaining two-thirds, the high level of activity is accompanied by irritability. You can recognize manic persons by their great urge to talk, their overflowing ideas and their relatively low need to sleep. They would prefer to do everything at once and immediately. They are extremely active professionally, socially, and sexually. They believe they have special talents or powers. It does not occur to them that certain deeds could have negative consequences. For example, they do not realize that they will not be able to pay off the debt from the purchase of a vintage car.

In addition to the classic mania with full expression of symptoms, there is the so-called "hypomania". In this case, the signs of mania are less pronounced.

I am worth nothing...

Depression is the absolute opposite of mania. The person affected is simply miserable. He is sad, feels useless and possibly wants to take his own life. Nothing gives him pleasure anymore. He doesn't care about things he used to care about. Concentrating or thinking is then extremely exhausting, which is why the affected person is hardly able to make decisions. He can't get himself up for anything and is constantly tired. Nevertheless, he sleeps little. During a depressive episode, the appetite may decrease. However, he can also go completely overboard. Accordingly, weight fluctuations occur. Affected persons also constantly reproach themselves for trivial things, feel guilty and worthless.

People with bipolar disorder sometimes experience "mixed" phases. In this case, manic and depressive symptoms occur together. This can have particularly fatal consequences when a negative self-image coincides with increased activity. The risk of suicide is then particularly high.

The tendency to extremes

If someone you don't know very well were to meet you during his manic phase, you probably wouldn't get the idea of a mental disorder. Someone who is so active and lively can't be sick. In the depressive phase, sufferers withdraw. Therefore, they hardly encounter anyone who might notice their bad mood. Only the family or close friends have a chance to notice the depression.

Bipolar disorder is often confused with other mental illnesses. For example, about two-thirds of those affected tend to abuse alcohol, drugs or medications. This is then often the primary diagnosis when they are taken to a psychiatric ward. The extreme feelings also promote unusual eating behavior. Sometimes sufferers eat a lot, sometimes they refuse almost any food. Anxiety and panic attacks can also occur. All these additional manifestations cloud the view of outsiders on the actual problem of the affective disorder.

The consequences of the unusual behavior during the depressive as well as the manic phases are often serious: The entire life of the affected person can gradually be destroyed. They sometimes destroy even their social and family relationships. For employers, they are usually unbearable in the short or long term. Ultimately, up to half of those affected commit at least one suicide attempt. Up to one third actually kill themselves in the course of their illness.

Causes and onset in young adulthood

The exact causes of bipolar disorder have not yet been exhaustively researched. What is certain is that there are familial clusters, which is why a genetic component is assumed. However, the trigger for the first depressive or manic phase is always an extreme life event. This can be severe stress or a traumatic experience. In the subsequent phases, there are then no specific causes. If the disorder remains untreated, it often continues with increasingly rapid successive phases. The symptom-free intermediate phases then become noticeably shorter.

Approximately one to two out of every one hundred people will develop bipolar disorder in the course of their lives. Around 75% of those affected experience their first episode before the age of 25. In retrospect, patients almost always recall first signs of extreme mood swings in their teens. It is very rare for a person over 40 to be newly diagnosed with bipolar disorder. Overall, men and women are affected about equally often.

Therapie - wozu?

Dealing with people suffering from bipolar disorder is extremely delicate. For example, they do not feel ill during manic phases - quite the opposite. In depressive phases, they tend to lack any motivation to do anything. They then believe, for example, that they are not worthy of therapy. In the symptom-free intermediate phases, they then actually have no problems. So motivating to therapy can be very difficult. If you suspect a bipolar disorder in a friend, you have to approach him with tact and patience. Ultimately, sufferers are more likely to end up in a psychiatric ward because of their extreme behavior during a manic episode or because of a suicide attempt than because they allow themselves to be persuaded into therapy.

Therapy itself is also complicated. The goal is to prevent further episodes. This is because each episode increases the likelihood of more and more manic and depressive episodes.

Both medication and classic psychotherapy are used in the therapy. Lithium has proven to be effective for phase prophylaxis. However, it quickly hits the kidneys, which is why older patients should only take it with great caution. The therapist also teaches the patient as much as possible about bipolar disorder. They must learn how to assess themselves and recognize new episodes at an early stage. Ideally, relatives also receive information about the illness and how to deal with the person affected. The main aim is to improve sleep with the help of relaxation techniques. The overall success rate is mixed: one year after an inpatient stay, around half of the patients are still fully compliant.

Bipolar disorder has a clear genetic component. About half of those with the disorder have family members who also suffer from bipolar disorder. It is not one particular gene that is causally responsible for this mental illness. Rather, experts believe that there is a complex gene pattern that has not yet been fully deciphered. Affected individuals also exhibit a physiological alteration in the balance of neurotransmitters. In particular, before the first mood swings occur, there is usually a special event in the life of the affected person. This can be great stress or a traumatic experience. In the following phases, such outbursts are no longer discernible. </p>

Recognizing bipolar disorder as a layperson is almost impossible. With people you rarely meet, you will most likely think the signs are a noticeable trait. With a person you know well, over time you may notice the extreme range of emotions. Sometimes the person is very quiet and withdrawn for weeks at a time. Maybe you don't see him at all for two or three months. When you do meet, you notice his rough thoughtfulness as well as a lack of drive. Six months later, the same person may contact you several times a day. They will be bubbling over with ideas and drive. At the same time, however, she is also easily irritated and reacts extremely even to small things. Based on this change in moods and behavior alone over months and years, you may suspect. </p>

The treatment of bipolar disorder with medication always has two different goals: On the one hand, the aim is to reduce the acute symptoms. On the other hand, further episodes are to be prevented. Lithium is the main drug used for this purpose. It is the best-known drug that can reduce both manic and depressive symptoms. It also has an antisuicidal effect. If lithium is contraindicated, for example due to kidney disease, psychiatrists prescribe anticonvulsants as an alternative. These include carbamazepine, valproate and lamotrigine. Antipsychotics are also used during acute mania. Quetiapine is also used for depressive phases. Classic treatment with antidepressants is not recommended for bipolar disorder because patients may switch to mania. </p>

The individual episodes in bipolar disorder can extend over very different periods of time. Depressive episodes last an average of three to six months. Manic phases are around two to four months. On an individual level, these periods can be quite different. As a rule, however, mania lasts less long than depression. The episodes themselves are composed of acute phase of illness and remission. In the acute phase, symptoms are fully developed, whereas in remission they gradually decline. </p>

Psychologists distinguish between different types of bipolar disorder. Bipolar I describes the classic alternation between depressive and manic phases. A patient from the Bipolar II group, on the other hand, fluctuates between depression and hypomania. This means that the manic symptoms are not fully developed in this patient. There is also the phenomenon of mixed phases. Here, both manic and depressive symptoms occur within a few hours. In „rapid cycling“, on the other hand, there is a relatively rapid succession of manic and depressive episodes. At least four clearly separated episodes occur within a year. </p>

Conclusion

The emotional life of people suffering from bipolar disorder fluctuates between two extremes. During a manic phase, they feel energetic, active and euphoric or irritable. If they go through a depressive episode, they are depressed, listless and feel worthless. There are symptom-free periods between these extreme mood states. The exact time course of the phases varies greatly from individual to individual. For laypersons, the disorder is very difficult to recognize. Many sufferers tend to abuse alcohol, drugs or medication, which appears to outsiders as a dominant disorder. Typically, bipolar disorder manifests between the ages of 20 and 30. The risk of suicide is very high with this mental illness. Nevertheless, those affected accept therapeutic measures very poorly on average. The primary goal of therapy is to prevent further episodes with the help of medication and psychotherapeutic interventions.

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